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Article

C282Y polymorphism in the HFE gene is associated with risk of breast cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013

Liu Xiaoyan, Lv Chunlei, Luan Xiaorong, Lv Ming

Abstract excerpt

The C282Y and H63D polymorphisms in the HFE gene have been implicated in susceptibility of breast cancer, but a number of studies have reported inconclusive results. The aim of this study is to investigate the association between the C282Y and H63D polymorphisms in the HFE gene and breast cancer risk by meta-analysis. We searched PubMed and Embase databases, covering all related studies until March 2, 2013....

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Source

Identifiers

PMID: 23681799
DOI: 10.1007/s13277-013-0833-9

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

C282Y polymorphism in the HFE gene is associated with risk of breast cancer.PMID 23681799Read ↗

Meta-Analysis of the Association between H63D and C282Y Polymorphisms in HFE and Cancer Risk.Semantic proximity Read ↗

HFE H63D mutation frequency shows an increase in Turkish women with breast cancer.Semantic proximity Read ↗

HFE gene C282Y variant is associated with colorectal cancer in Caucasians: a meta-analysis.Semantic proximity Read ↗

HFE Gene Variants' Impact on Anthracycline-Based Chemotherapy-Induced Subclinical Cardiotoxicity.Semantic proximity Read ↗

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer.Semantic proximity Read ↗

HFE mutations and risk of coronary heart disease in middle-aged women.Semantic proximity Read ↗

Implicating the H63D polymorphism in the HFE gene in increased incidence of solid cancers: a meta-analysis.Semantic proximity Read ↗

The risk of new-onset cancer associated with HFE C282Y and H63D mutations: evidence from 87,028 participants.Semantic proximity Read ↗

Association between C282Y and H63D mutations of the HFE gene with hepatocellular carcinoma in European populations: a meta-analysis.Semantic proximity Read ↗

Impact of hemochromatosis gene (HFE) mutations on epithelial ovarian cancer risk and prognosis.Semantic proximity Read ↗

The association between the C282Y and H63D polymorphisms of HFE gene and the risk of Parkinson's disease: A meta-analysis.Semantic proximity Read ↗

Cancer risk in HFE C282Y homozygotes: results from the HUNT 2 study.Semantic proximity Read ↗

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