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Article

Association between C282Y and H63D mutations of the HFE gene with hepatocellular carcinoma in European populations: a meta-analysis.

Journal of experimental & clinical cancer research : CR - 2 Mar 2010

Jin Fei, Qu Li-Shuai, Shen Xi-Zhong

Abstract excerpt

BACKGROUND: Hereditary hemochromatosis (HH) is an autosomal recessive disorder mainly associated with homozygosity for the C282Y and H63D mutations in the hemochromatosis (HFE) gene. The reports about the C282Y and H63D mutations and hepatocellular carninoma (HCC) were controversial. To clarify the relationship between C282Y and H63D mutations and HCC, a meta-analysis including nine studies (1102 HCC cases and...

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Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemochromatosis Protein

Share to Histocompatibility Antigens Class I

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 20196837
DOI: 10.1186/1756-9966-29-18
PMCID: PMC2845109

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Association between C282Y and H63D mutations of the HFE gene with hepatocellular carcinoma in European populations: a meta-analysis.PMID 20196837Read ↗

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