Article
Hemochromatosis (HFE) gene mutations and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
Carcinogenesis - 1 Jun 2013
Agudo Antonio, Bonet Catalina, Sala Núria, Muñoz Xavier, Aranda Núria, Fonseca-Nunes Ana, Clavel-Chapelon Françoise, Boutron-Ruault Marie Christine, Vineis Paolo, Panico Salvatore, Palli Domenico, Tumino Rosario, Grioni Sara, Quirós J Ramón, Molina Esther, Navarro Carmen, Barricarte Aurelio, Chamosa Saioa, Allen Naomi E, Khaw Kay-Tee, Bueno-de-Mesquita H Bas, Siersema Peter D, Numans Mattijs E, Trichopoulou Antonia, Lagiou Pagona, Trichopoulos Dimitrios, Kaaks Rudof, Canzian Federico, Boeing Heiner, Meidtner Karina, Johansson Mattias, Sund Malin, Manjer Jonas, Overvad Kim, Tjonneland Anne, Lund Eiliv, Weiderpass Elisabete, Jenab Mazda, Fedirko Veronika, Offerhaus G Johan A, Riboli Elio, González Carlos A, Jakszyn Paula
Abstract excerpt
Hereditary hemochromatosis (HH) is a strong risk factor for hepatocellular cancer, and mutations in the HFE gene associated with HH and iron overload may be related to other tumors, but no studies have been reported for gastric cancer (GC). A nested case-control study was conducted within the European Prospective Investigation into Cancer and Nutrition (EPIC), including 365 incident gastric adenocarcinoma and...
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