Article
Clinicopathologic and prognostic associations of KRAS and BRAF mutations in small intestinal adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2016
Jun Sun-Young, Kim Misung, Jin Gu Mi, Kyung Bae Young, Chang Hee-Kyung, Sun Jung Eun, Jang Kee-Taek, Kim Jihun, Yu Eunsil, Woon Eom Dae, Hong Seung-Mo
Abstract excerpt
Activating KRAS and/or BRAF mutations have been identified as predictors of resistance to anti-epidermal growth factor receptor (EGFR) chemotherapy in colorectal cancer. But the status of KRAS and BRAF mutations and their clinicopathologic and prognostic significance has not been extensively evaluated in small intestinal adenocarcinomas. In this work, the KRAS and BRAF genes in 190 surgically resected small...
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