Article
Driver and targetable alterations in Chinese patients with small bowel carcinoma.
Journal of cancer research and clinical oncology - 1 Aug 2023
Li Jun, Li Xiaomo, Dong Ningning, Yan Shu, Jing Chao, Ma Tonghui, Li Wei, Zhang Chenghai, Cai Yi, Deng Wei
Abstract excerpt
PURPOSE: Small bowel carcinoma (SBA) is a rare gastrointestinal cancer with a poor prognosis. Recent genomic profiling studies revealed that the landscape of molecular alterations in SBA was distinct from colorectal cancer (CRC) and gastric cancer (GC). To explore driver and targetable alterations in SBA, we performed next-generation sequencing in 107 Chinese SBA patients. METHODS: DNA from paraffin-embedded...
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