Article
The prognostic significance of KRAS and BRAF mutation status in Korean colorectal cancer patients.
BMC cancer - 5 Jun 2017
Won Daeyoun David, Lee Jae Im, Lee In Kyu, Oh Seong-Taek, Jung Eun Sun, Lee Sung Hak
Abstract excerpt
BACKGROUND: BRAF and KRAS mutations are well-established biomarkers in anti-EGFR therapy. However, the prognostic significance of these mutations is still being examined. We determined the prognostic value of BRAF and KRAS mutations in Korean colorectal cancer (CRC) patients. METHODS: From July 2010 to September 2013, 1096 patients who underwent surgery for CRC at Seoul St. Mary's Hospital were included in the...
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