Article
The prognostic significance of KRAS and BRAF mutation status in Korean colorectal cancer patients.
BMC cancer - 5 Jun 2017
Won Daeyoun David, Lee Jae Im, Lee In Kyu, Oh Seong-Taek, Jung Eun Sun, Lee Sung Hak
Abstract excerpt
BACKGROUND: BRAF and KRAS mutations are well-established biomarkers in anti-EGFR therapy. However, the prognostic significance of these mutations is still being examined. We determined the prognostic value of BRAF and KRAS mutations in Korean colorectal cancer (CRC) patients. METHODS: From July 2...
Topics
- Colorectal Neoplasms
- Disease-Free Survival
- Female
- Humans
- Male
- Microsatellite Instability
- Middle Aged
- Mutation
- Prognosis
- Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins p21(ras)
- Republic of Korea
- Retrospective Studies