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Article

A comprehensive study of polymorphic sites along the HLA-G gene: implication for gene regulation and evolution.

Molecular biology and evolution - 1 Nov 2011

Castelli Erick C, Mendes-Junior Celso T, Veiga-Castelli Luciana C, Roger Michel, Moreau Philippe, Donadi Eduardo A

Abstract excerpt

HLA-G molecule plays an important role on immune response regulation and has been implicated on the inhibition of T and natural killer cell cytolytic function and inhibition of allogeneic T-cell proliferation. Due to its immune-modulator properties, the HLA-G gene expression has been associated with the outcome of allograft and of autoimmune, infectious, and malignant disorders. Several lines of evidence indicate...

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PMID: 21622995
DOI: 10.1093/molbev/msr138

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