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Article

In Silico Analysis of the Structural and Biochemical Features of the NMD Factor UPF1 in Ustilago maydis.

PloS one - 1 Jan 2016

Martínez-Montiel Nancy, Morales-Lara Laura, Hernández-Pérez Julio M, Martínez-Contreras Rebeca D

Abstract excerpt

The molecular mechanisms regulating the accuracy of gene expression are still not fully understood. Among these mechanisms, Nonsense-mediated Decay (NMD) is a quality control process that detects post-transcriptionally abnormal transcripts and leads them to degradation. The UPF1 protein lays at the heart of NMD as shown by several structural and functional features reported for this factor mainly for Homo sapiens...

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Share to Crystallography, X-Ray
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Dynamics Simulation

Share to Nonsense Mediated mRNA Decay

Share to Protein Processing, Post-Translational

Share to Protein Structure, Secondary

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Source

Open in PubMed Open full text

Identifiers

PMID: 26863136
DOI: 10.1371/journal.pone.0148191
PMCID: PMC4749658

Genes

UPF1
UPF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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In Silico Analysis of the Structural and Biochemical Features of the NMD Factor UPF1 in Ustilago maydis.PMID 26863136Read ↗

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