Article
Conditional Expression of the Androgen Receptor Increases Susceptibility of Bladder Cancer in Mice.
PloS one - 1 Jan 2016
Johnson Daniel T, Hooker Erika, Luong Richard, Yu Eun-Jeong, He Yongfeng, Gonzalgo Mark L, Sun Zijie
Abstract excerpt
Bladder cancer represents a significant human tumor burden, accounting for about 7.7% and 2.4% of all cancer cases in males and females, respectively. While men have a higher risk of developing bladder cancer, women tend to present at a later stage of disease and with more aggressive tumors. Previous studies have suggested a promotional role of androgen signaling in enhancing bladder cancer development. To...
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