Article
BBN-driven urinary bladder cancer mouse model.
Methods in cell biology - 1 Jan 2021
Korac-Prlic Jelena, Degoricija Marina, Vilović Katarina, Vujević Sandra, Terzić Janoš
Abstract excerpt
Around 3% of new cancer diagnoses and 2% of all cancer deaths every year are caused by urinary bladder cancer (BC). This indicates a great need for intensive studying of BC by using different approaches including indispensable mice models. The most common preclinical mouse model of bladder carcinogenesis relies on the use of a nitrosamine compound, N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) which causes...
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