Article
No genotoxicity in rat blood cells upon 3- or 6-month inhalation exposure to CeO2 or BaSO4 nanomaterials.
Mutagenesis - 1 Jan 2017
Cordelli Eugenia, Keller Jana, Eleuteri Patrizia, Villani Paola, Ma-Hock Lan, Schulz Markus, Landsiedel Robert, Pacchierotti Francesca
Abstract excerpt
In the course of a 2-year combined chronic toxicity-carcinogenicity study performed according to Organisation for Economic Co-operation and Development (OECD) Test Guideline 453, systemic (blood cell) genotoxicity of two OECD representative nanomaterials, CeO2 NM-212 and BaSO4 upon 3- or 6-month inhalation exposure to rats was assessed. DNA effects were analysed in leukocytes using the alkaline Comet assay, gene...
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