Article
Evaluation of the genotoxic potential of single-wall carbon nanotubes by using a battery of in vitro and in vivo genotoxicity assays.
Regulatory toxicology and pharmacology : RTP - 1 Nov 2011
Naya Masato, Kobayashi Norihiro, Mizuno Kohei, Matsumoto Kyomu, Ema Makoto, Nakanishi Junko
Abstract excerpt
The genotoxic potential of a high purity sample of single-wall carbon nanotubes (SWCNTs) was evaluated using a battery of in vitro and in vivo genotoxicity assays. These comprised a bacterial reverse mutation test (Ames test), an in vitro chromosomal aberration test, and an in vivo mouse bone marrow micronucleus test. The SWCNTs exerted no genotoxicity in Salmonella typhimurium TA97, TA98, TA100, and TA1535, or...
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