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Article

Lineage-related cytotoxicity and clonogenic profile of 1,4-benzoquinone-exposed hematopoietic stem and progenitor cells.

Toxicology and applied pharmacology - 1 Apr 2015

Chow Paik Wah, Abdul Hamid Zariyantey, Chan Kok Meng, Inayat-Hussain Salmaan Hussain, Rajab Nor Fadilah

Abstract excerpt

Hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) are sensitive targets for benzene-induced hematotoxicity and leukemogenesis. The impact of benzene exposure on the complex microenvironment of HSCs and HPCs remains elusive. This study aims to investigate the mechanism linking benzene exposure to targeting HSCs and HPCs using phenotypic and clonogenic analyses. Mouse bone marrow (BM) cells...

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Identifiers

PMID: 25645895
DOI: 10.1016/j.taap.2015.01.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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