Article
Impact of organic pollutants on phenotype and gene expression in human breast cancer cells.
Journal of applied toxicology : JAT - 1 May 2026
Confortin Camila, Amancio Heloisa, da Luz Jessica Zablocki, de Almeida Roque Aliciane, de Souza Tugstênio Lima, Vargas José Eduardo, de Oliveira Ribeiro Ciro Alberto, Neto Francisco Filipak
Abstract excerpt
Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long-term exposure alters cell phenotype. Therefore, the current study investigated whether exposure to the OP perfluorooctanoic acid (Pfoa: 0.01, 0.1, and...
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