A Novel Selectable Islet 1 Positive Progenitor Cell Reprogrammed to Expandable and Functional Smooth Muscle Cells.

doi:10.1002/stem.2319

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Article

A Novel Selectable Islet 1 Positive Progenitor Cell Reprogrammed to Expandable and Functional Smooth Muscle Cells.

Stem cells (Dayton, Ohio) - 1 May 2016

Turner Elizabeth C, Huang Chien-Ling, Sawhney Neha, Govindarajan Kalaimathi, Clover Anthony J P, Martin Kenneth, Browne Tara C, Whelan Derek, Kumar Arun H S, Mackrill John J, Wang Shaohua, Schmeckpeper Jeffrey, Stocca Alessia, Pierce William G, Leblond Anne-Laure, Cai Liquan, O'Sullivan Donnchadh M, Buneker Chirlei K, Choi Janet, MacSharry John, Ikeda Yasuhiro, Russell Stephen J, Caplice Noel M

Abstract excerpt

Disorders affecting smooth muscle structure/function may require technologies that can generate large scale, differentiated and contractile smooth muscle cells (SMC) suitable for cell therapy. To date no clonal precursor population that provides large numbers of differentiated SMC in culture has been identified in a rodent. Identification of such cells may also enhance insight into progenitor cell fate decisions...

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PMID: 26840832
DOI: 10.1002/stem.2319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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