Article
Porcine skeletal muscle-derived multipotent PW1pos/Pax7neg interstitial cells: isolation, characterization, and long-term culture.
Stem cells translational medicine - 1 Jun 2014
Lewis Fiona C, Henning Beverley J, Marazzi Giovanna, Sassoon David, Ellison Georgina M, Nadal-Ginard Bernardo
Abstract excerpt
Developing effective strategies for the regeneration of solid tissue requires an understanding of the biology underlying the tissue's endogenous repair mechanisms. PW1/Peg3(pos)/Pax7(neg) skeletal muscle-derived interstitial progenitor cells (PICs) were first identified recently in the interstitium of murine skeletal muscle and shown to contribute to muscle fiber regeneration in vivo. PICs, therefore, represent a...
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