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Skeletal muscle-derived interstitial progenitor cells (PICs) display stem cell properties, being clonogenic, self-renewing, and multi-potent in vitro and in vivo

4 Jul 2017

Abstract excerpt

The development of cellular therapies to treat muscle wastage with disease or age is paramount. Resident muscle satellite cells are not currently regarded as a viable cell source due to their limited migration and growth capability ex vivo. This study investigated the potential of muscle-derived PW1 + /Pax7 – interstitial progenitor cells (PICs) as a source of tissue-specific stem/progenitor cells with stem cell...

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PMID: 28676130
DOI: 10.1186/s13287-017-0612-4

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