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Article

Biology of Isl1+ cardiac progenitor cells in development and disease.

1 Mar 2007

Abstract excerpt

The LIM-homeodomain transcription factor Islet-1 (Isl1) marks a cell population which makes a substantial contribution to the embryonic heart. Isl1 expression is downregulated as soon as the cells adopt a differentiated phenotype, suggesting that this transcription factor delineates a cardiogenic progenitor cell population. Taking advantage of this developmental lineage marker, we have identified in the postnatal...

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Identifiers

PMID: 17380308
DOI: 10.1007/s00018-007-6520-5

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Biology of Isl1+ cardiac progenitor cells in development and disease.PMID 17380308Read ↗

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