Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders.

doi:10.1038/ncomms10594

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders.

Nature communications - 3 Feb 2016

Nakazawa Takanobu, Hashimoto Ryota, Sakoori Kazuto, Sugaya Yuki, Tanimura Asami, Hashimotodani Yuki, Ohi Kazutaka, Yamamori Hidenaga, Yasuda Yuka, Umeda-Yano Satomi, Kiyama Yuji, Konno Kohtarou, Inoue Takeshi, Yokoyama Kazumasa, Inoue Takafumi, Numata Shusuke, Ohnuma Tohru, Iwata Nakao, Ozaki Norio, Hashimoto Hitoshi, Watanabe Masahiko, Manabe Toshiya, Yamamoto Tadashi, Takeda Masatoshi, Kano Masanobu

Abstract excerpt

Intracellular trafficking of receptor proteins is essential for neurons to detect various extracellular factors during the formation and refinement of neural circuits. However, the precise mechanisms underlying the trafficking of neurotrophin receptors to synapses remain elusive. Here, we demonstrate that a brain-enriched sorting nexin, ARHGAP33, is a new type of regulator for the intracellular trafficking of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Vesicular Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Spines

Share to GTPase-Activating Proteins

Share to Hippocampus

Share to Patch-Clamp Techniques

Share to Receptor, trkB

Share to Sorting Nexins

Share to Synapses

Source

Open in PubMed Open full text

Identifiers

PMID: 26839058
DOI: 10.1038/ncomms10594
PMCID: PMC4742909

Genes

ARHGAP33
SORT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders.PMID 26839058Read ↗

Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric DisordersSemantic proximity Read ↗

Sorting Out Sorting Nexins Functions in the Nervous System in Health and DiseaseSemantic proximity Read ↗

Schizophrenia-linked protein tSNARE1 regulates endolysosomal trafficking in cortical neuronsSemantic proximity Read ↗

A neuron type-specific microexon in <i>Ank3</i> /ankyrin-G modulates calcium activity and neuronal excitabilitySemantic proximity Read ↗

The Reelin Receptor ApoER2 is a Cargo for the Adaptor Protein Complex AP-4: Implications for Hereditary Spastic ParaplegiaSemantic proximity Read ↗

Haploinsufficiency of intraflagellar transport protein 172 causes autism-like behavioral phenotypes in mice through BDNF.Semantic proximity Read ↗

The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review.Semantic proximity Read ↗

Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neuronsSemantic proximity Read ↗

SORT1 Mutation Resulting in Sortilin Deficiency and p75(NTR) Upregulation in a Family With Essential Tremor.Semantic proximity Read ↗

An emerging role for TARPs in neuropsychiatric disorders.Semantic proximity Read ↗

Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function.Semantic proximity Read ↗

Regulation of <i>NTRK2</i> alternative splicing by PRPF40B controls neural differentiation and synaptic plasticitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.