Article

A neuron type-specific microexon in <i>Ank3</i> /ankyrin-G modulates calcium activity and neuronal excitability

2025-12-13

Abstract excerpt

<h4>ABSTRACT</h4> Recent studies have revealed many alternative exons differentially spliced across diverse neuron types in the mammalian brain, but their links to neuronal physiology remain unclear. Here we characterize a deeply conserved microexon E35a in Ank3 encoding ankyrin-G (AnkG), a multifaceted adaptor protein best known as a master organizer of the axon initial segment (AIS) and as a leading genetic ri...

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Literature Corpus work: 18187488-1ef1-5569-8638-ac107162bd21
DOI: 10.64898/2025.12.12.693948

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