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Article

Deficits in the Proline-Rich Synapse-Associated Shank3 Protein in Multiple Neuropsychiatric Disorders

11 Dec 2017

Abstract excerpt

Signaling between neurons in the human central nervous system (CNS) is accomplished through a highly interconnected network of pre-synaptic and post-synaptic elements essential in the conveyance of electrical and neurochemical information. One recently characterized core post-synaptic element essential to the efficient operation of this complex network is a relatively abundant ~184.7 kDa proline-rich...

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PMID: 29321759
DOI: 10.3389/fneur.2017.00670

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