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Article

Prevention of SHIV transmission by topical IFN-β treatment.

Mucosal immunology - 1 Nov 2016

Veazey R S, Pilch-Cooper H A, Hope T J, Alter G, Carias A M, Sips M, Wang X, Rodriguez B, Sieg S F, Reich A, Wilkinson P, Cameron M J, Lederman M M

Abstract excerpt

Understanding vaginal and rectal HIV transmission and protective cellular and molecular mechanisms is critical for designing new prevention strategies, including those required for an effective vaccine. The determinants of protection against HIV infection are, however, poorly understood. Increasing evidence suggest that innate immune defenses may help protect mucosal surfaces from HIV transmission in highly...

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Source

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Identifiers

PMID: 26838048
DOI: 10.1038/mi.2015.146
PMCID: PMC4972705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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