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Article

Hyperuricaemia: contributions of urate transporter ABCG2 and the fractional renal clearance of urate.

Annals of the rheumatic diseases - 1 Jul 2016

Kannangara Diluk R W, Phipps-Green Amanda J, Dalbeth Nicola, Stamp Lisa K, Williams Kenneth M, Graham Garry G, Day Richard O, Merriman Tony R

Abstract excerpt

OBJECTIVE: To investigate the contributions towards hyperuricaemia of known risk factors, focusing on fractional (renal) clearance of urate (FCU) and variation in the ATP-binding cassette transporter, sub-family G 2 (ABCG2) gene. METHODS: The contributions of age, sex, ancestry, Q141K genotype for ABCG2, FCU, sugar-sweetened beverage and alcohol consumption, metabolic syndrome disorders and measures of renal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26835700
DOI: 10.1136/annrheumdis-2015-208111

Genes

ABCG2

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