Article
The association between genetic polymorphisms in ABCG2 and SLC2A9 and urate: an updated systematic review and meta-analysis.
BMC medical genetics - 21 Oct 2020
Lukkunaprasit Thitiya, Rattanasiri Sasivimol, Turongkaravee Saowalak, Suvannang Naravut, Ingsathit Atiporn, Attia John, Thakkinstian Ammarin
Abstract excerpt
BACKGROUND: Replication studies showed conflicting effects of ABCG2 and SLC2A9 polymorphisms on gout and serum urate. This meta-analysis therefore aimed to pool their effects across studies. METHODS: Studies were located from MEDLINE and Scopus from inception to 17th June 2018. Observational studies in adults with any polymorphism in ABCG2 or SLC2A9, and outcome including gout, hyperuricemia, and serum urate were...
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