Are polymorphisms affecting serum urate, renal urate handling and alcohol intake associated with co-morbidities in gout cases? A case-control study using data from the UK Biobank.

doi:10.1007/s00296-022-05148-7

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Are polymorphisms affecting serum urate, renal urate handling and alcohol intake associated with co-morbidities in gout cases? A case-control study using data from the UK Biobank.

Rheumatology international - 1 Sept 2022

Sandoval-Plata Gabriela, Morgan Kevin, Abhishek Abhishek

Abstract excerpt

To examine the association between common comorbidities, eGFR and loci involved in the hyperuricaemia-gout transition. This study was conducted in people with gout from the UK Biobank. Logistic regression was used to examine the association between self-reported physician-diagnosed hypertension, diabetes, hypercholesterolemia and ischaemic heart disease (IHD) with the following variants: rs1260326(GCKR),...

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PMID: 35633389
DOI: 10.1007/s00296-022-05148-7
PMCID: PMC9349305

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