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Article

ABCG2 as a therapeutic target candidate for gout.

Expert opinion on therapeutic targets - 1 Feb 2018

Fujita Kyoko, Ichida Kimiyoshi

Abstract excerpt

INTRODUCTION: Hyperuricemia (chronically elevated serum uric acid) is the main pathology underlying the development of gout, the most common inflammatory arthropathy. Management of these conditions therefore relies on controlling serum uric acid levels. ATP-binding cassette transporter, sub-family G, member 2 (ABCG2/BCRP) is a well-studied urate transporter expressed on apical membranes in several tissues,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29264928
DOI: 10.1080/14728222.2018.1420167

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ABCG2 as a therapeutic target candidate for gout.PMID 29264928Read ↗

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Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population.Semantic proximity Read ↗

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ABCG2/BCRP dysfunction as a major cause of gout.Semantic proximity Read ↗

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