Article
The importance of having two X chromosomes.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Feb 2016
Arnold Arthur P, Reue Karen, Eghbali Mansoureh, Vilain Eric, Chen Xuqi, Ghahramani Negar, Itoh Yuichiro, Li Jingyuan, Link Jenny C, Ngun Tuck, Williams-Burris Shayna M
Abstract excerpt
Historically, it was thought that the number of X chromosomes plays little role in causing sex differences in traits. Recently, selected mouse models have been used increasingly to compare mice with the same type of gonad but with one versus two copies of the X chromosome. Study of these models demonstrates that mice with one X chromosome can be strikingly different from those with two X chromosomes, when the...
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