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Article

Greater improvement in LRRK2 G2019S patients undergoing Subthalamic Nucleus Deep Brain Stimulation compared to non-mutation carriers.

BMC neuroscience - 1 Feb 2016

Sayad Massiva, Zouambia Mohamed, Chaouch Malika, Ferrat Farida, Nebbal Mustapha, Bendini Mohamed, Lesage Suzanne, Brice Alexis, Brahim Errahmani Mohamed, Asselah Boualem

Abstract excerpt

BACKGROUND: Bilateral subthalamic nucleus deep brain stimulation (STN-DBS) of parkinson's disease (PD) patients has demonstrated to improve motor performance and to reduce dopa-induced dyskinesia. An association between the occurrence of dyskinesias and LRRK2 (leucine-rich repeat kinase 2) G2019S gene mutations has recently been suggested. The aim of this study is to discover the impact of the G2019S mutation...

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Identifiers

PMID: 26831335
DOI: 10.1186/s12868-016-0240-4
PMCID: PMC4736184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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