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Genetic background and outcome of Deep Brain Stimulation in Parkinson's disease.

Parkinsonism & related disorders - 1 Jul 2019

Rizzone Mario Giorgio, Martone Tiziana, Balestrino Roberta, Lopiano Leonardo

Abstract excerpt

Deep Brain Stimulation (DBS) is a well-established therapeutic option for patients with Parkinson's disease (PD). The high variability observed in the outcome demands better prediction criteria to select candidate patients that may obtain the best results from DBS. Recent advances in genetics have provided important tools to investigate variability in clinical features of PD patients, creating the possibility to...

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PMID: 30121162
DOI: 10.1016/j.parkreldis.2018.08.006

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PRKN

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