Article
15-Year Subthalamic Deep Brain Stimulation outcome in a Parkinson's disease patient with Parkin gene mutation: a case report.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Aug 2023
Covolo Anna, Imbalzano Gabriele, Artusi Carlo Alberto, Montanaro Elisa, Ledda Claudia, Bozzali Marco, Rizzone Mario Giorgio, Zibetti Maurizio, Martone Tiziana, Lopiano Leonardo, Romagnolo Alberto
Abstract excerpt
INTRODUCTION: Parkinson's Disease (PD) patients with Parkin gene (PRKN) mutations show good response to subthalamic deep brain stimulation (STN-DBS). Currently, the longest follow-up available of these patients is 6 years. We report a very long-term outcome (more than 15 years) of a STN-DBS-treated patient with a compound heterozygous deletion of exons 3 and 11 of the PRKN gene. CASE REPORT: In 1993, a...
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