Article
The Genetic Architecture of Murine Glutathione Transferases.
PloS one - 1 Jan 2016
Lu Lu, Pandey Ashutosh K, Houseal M Trevor, Mulligan Megan K
Abstract excerpt
Glutathione S-transferase (GST) genes play a protective role against oxidative stress and may influence disease risk and drug pharmacokinetics. In this study, massive multiscalar trait profiling across a large population of mice derived from a cross between C57BL/6J (B6) and DBA2/J (D2)--the BXD family--was combined with linkage and bioinformatic analyses to characterize mechanisms controlling GST expression and...
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