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Article

Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits.

PloS one - 1 Jan 2012

McKnite Autumn M, Perez-Munoz Maria Elisa, Lu Lu, Williams Evan G, Brewer Simon, Andreux Pénélope A, Bastiaansen John W M, Wang Xusheng, Kachman Stephen D, Auwerx Johan, Williams Robert W, Benson Andrew K, Peterson Daniel A, Ciobanu Daniel C

Abstract excerpt

The gastrointestinal tract harbors a complex and diverse microbiota that has an important role in host metabolism. Microbial diversity is influenced by a combination of environmental and host genetic factors and is associated with several polygenic diseases. In this study we combined next-generation sequencing, genetic mapping, and a set of physiological traits of the BXD mouse population to explore genetic...

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Identifiers

PMID: 22723961
DOI: 10.1371/journal.pone.0039191
PMCID: PMC3377628

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Source receipt: pubmed, retrieved 7 Sept 2026.

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