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Article

Genetic heterogeneity of the human glutathione transferases: a complex of gene families.

Pharmacology & therapeutics - 1 Jan 1990

Board P, Coggan M, Johnston P, Ross V, Suzuki T, Webb G

Abstract excerpt

The glutathione transferases (GSTs) are involved in the metabolism of a wide range of compounds of both exogenous and endogenous origin. There is evidence that deficiency of GST may increase sensitivity to certain environmentally derived carcinogens. In contrast, elevated expression has been implicated in resistance to therapeutic drugs. The GSTs are the products of several gene families. This review summarizes...

Topics

Animals
Genes
Glutathione Transferase
Humans
Hybridization, Genetic
Isoenzymes
Liver
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2084706
DOI: 10.1016/0163-7258(90)90054-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2084706-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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