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Article

Required Role of Apoptotic Myogenic Precursors and Toll‐like Receptor Stimulation for the Establishment of Autoimmune Myositis in Experimental Murine Models

10 Dec 2014

Abstract excerpt

OBJECTIVE: Muscle regeneration is a hallmark of the idiopathic inflammatory myopathies (IIMs), a group of autoimmune disorders that are characterized by leukocyte infiltration and dysfunction of the skeletal muscle. Despite detailed studies describing the clinical and histopathologic features of IIMs, the immunopathogenesis of these disorders remains undefined. The aim of this study was to investigate the...

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PMID: 25504878
DOI: 10.1002/art.38985

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