Article
Muscles provide protection during microbial infection by activating innate immune response pathways in Drosophila and zebrafish.
Disease models & mechanisms - 1 Jun 2016
Chatterjee Arunita, Roy Debasish, Patnaik Esha, Nongthomba Upendra
Abstract excerpt
Muscle contraction brings about movement and locomotion in animals. However, muscles have also been implicated in several atypical physiological processes including immune response. The role of muscles in immunity and the mechanism involved has not yet been deciphered. In this paper, using Drosophila indirect flight muscles (IFMs) as a model, we show that muscles are immune-responsive tissues. Flies with...
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