Article
Animal models of inflammatory myopathy.
Current rheumatology reports - 1 Jun 2012
Ascherman Dana P
Abstract excerpt
The idiopathic inflammatory myopathies (IIMs) represent a heterogeneous group of disorders characterized by mononuclear cell infiltration of muscle and varying degrees of muscle dysfunction. To better understand the pathogenesis of these diseases, investigators have devised a number of infectious, genetic, and antigen-induced animal models that replicate different aspects of muscle involvement. Although the...
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