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Article

Genetic analysis of the kinome and phosphatome in cancer.

Cellular and molecular life sciences : CMLS - 1 Sept 2005

Arena S, Benvenuti S, Bardelli A

Abstract excerpt

Protein phosphorylation is a well-characterized biochemical process for reversible regulation of protein activity. Protein kinases and protein phosphatases are the key complementary players in this process, and through their coordinated activity cell homeostasis is tightly controlled. If these enzymes display aberrant activity, cells may undergo unrestrained growth, thus giving rise to complex diseases such as...

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Identifiers

PMID: 16132230
DOI: 10.1007/s00018-005-5205-1
PMCID: PMC11139117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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