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Targeting the Breast Cancer Kinome

17 May 2016

Abstract excerpt

Protein kinases are highly tractable targets for the treatment of many cancers including breast cancer, due to their essential role in tumor cell proliferation and survival. Sequencing of the breast cancer genome and transcriptome has defined breast cancer as a heterogeneous disease that is classified into five molecular subtypes: luminal A, luminal B, HER2-enriched, basal-like, and claudin-low. Each subtype...

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PMID: 27186656
DOI: 10.1002/jcp.25427

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