Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice.

Virology journal - 27 Jan 2016

Leist Sarah R, Kollmus Heike, Hatesuer Bastian, Lambertz Ruth L O, Schughart Klaus

Abstract excerpt

BACKGROUND: Previously, we performed a quantitative trait locus (QTL) mapping study in BXD recombinant inbred mice to identify host genetic factors that confer resistance to influenza A virus infection. We found Lst1 (leukocyte specific transcript 1) as one of the most promising candidate genes in the Qivr17-2 locus because it is non-functional in DBA/2 J mice. Several studies have proposed that LST1 plays a role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Susceptibility
Share to Host-Pathogen Interactions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Influenza A Virus, H1N1 Subtype

Share to Intracellular Signaling Peptides and Proteins

Share to Mice, Inbred DBA

Share to Mice, Knockout

Share to Orthomyxoviridae Infections

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 26817701
DOI: 10.1186/s12985-016-0471-0
PMCID: PMC4729168

Genes

LST1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice.PMID 26817701Read ↗

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.Semantic proximity Read ↗

Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.Semantic proximity Read ↗

Expression Quantitative Trait Loci for Extreme Host Response to Influenza A in Pre-Collaborative Cross MiceSemantic proximity Read ↗

Genetic regulation of homeostatic immune architecture in the lungs of Collaborative Cross miceSemantic proximity Read ↗

Mapping of clinical and expression quantitative trait loci in a sex-dependent effect of host susceptibility to mouse-adapted influenza H3N2/HK/1/68.Semantic proximity Read ↗

An ancient retrotransposon provides species-specific tuning of IL-18 inflammatory signalingSemantic proximity Read ↗

A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in miceSemantic proximity Read ↗

Multigenic control of resistance to Sendai virus infection in mice.Semantic proximity Read ↗

Regulation of Inflammatory Response by Transmembrane Adaptor Protein LST1.Semantic proximity Read ↗

An updated systematic review of the role of host genetics in susceptibility to influenza.Semantic proximity Read ↗

Mapping of genetic modulators of natural resistance to infection with Salmonella typhimurium in wild-derived mice.Semantic proximity Read ↗

Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.