Article
Mapping of clinical and expression quantitative trait loci in a sex-dependent effect of host susceptibility to mouse-adapted influenza H3N2/HK/1/68.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2012
Boivin Gregory A, Pothlichet Julien, Skamene Emil, Brown Earl G, Loredo-Osti J Concepción, Sladek Robert, Vidal Silvia M
Abstract excerpt
Seasonal influenza outbreaks and recurrent influenza pandemics present major challenges to public health. By studying immunological responses to influenza in different host species, it may be possible to discover common mechanisms of susceptibility in response to various influenza strains. This could lead to novel therapeutic targets with wide clinical application. Using a mouse-adapted strain of influenza...
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