Article
Mapping of genetic modulators of natural resistance to infection with Salmonella typhimurium in wild-derived mice.
Genomics - 15 Jan 1998
Sebastiani G, Olien L, Gauthier S, Skamene E, Morgan K, Gros P, Malo D
Abstract excerpt
Despite antibiotic therapy and vaccination programs, microbial diseases continue to be the leading cause of morbidity and mortality worldwide. The genetic basis of the host response to infection is complex, and its understanding has been facilitated through the study of mouse models of human infe...
Topics
- Animals
- Animals, Wild
- Carrier Proteins
- Cation Transport Proteins
- Chromosome Mapping
- Crosses, Genetic
- Disease Susceptibility
- Genetic Linkage
- Genotype
- Immunity, Innate
- Membrane Proteins
- Mice
- Mice, Inbred A
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Quantitative Trait, Heritable
- Salmonella Infections, Animal
- Salmonella typhimurium