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Article

Mapping of genetic modulators of natural resistance to infection with Salmonella typhimurium in wild-derived mice.

Genomics - 15 Jan 1998

Sebastiani G, Olien L, Gauthier S, Skamene E, Morgan K, Gros P, Malo D

Abstract excerpt

Despite antibiotic therapy and vaccination programs, microbial diseases continue to be the leading cause of morbidity and mortality worldwide. The genetic basis of the host response to infection is complex, and its understanding has been facilitated through the study of mouse models of human infectious diseases. Genetic variation in resistance of mice to infection with Salmonella typhimurium has been recognized...

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PMID: 9479490
DOI: 10.1006/geno.1997.5116

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