Article
Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.
BMC genomics - 20 Aug 2012
Nedelko Tatiana, Kollmus Heike, Klawonn Frank, Spijker Sabine, Lu Lu, Heßman Manuela, Alberts Rudi, Williams Robert W, Schughart Klaus
Abstract excerpt
BACKGROUND: There is strong but mostly circumstantial evidence that genetic factors modulate the severity of influenza infection in humans. Using genetically diverse but fully inbred strains of mice it has been shown that host sequence variants have a strong influence on the severity of influenza...
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