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Article

The influence of gene-chronic hepatitis C virus infection on hepatic fibrosis and steatosis.

Diagnostic microbiology and infectious disease - 1 Jun 2020

Magri Mariana Cavalheiro, Manchiero Caroline, Prata Thamiris Vaz Gago, Nunes Arielle Karen da Silva, Oliveira Junior José Santos de, Dantas Bianca Peixoto, Tengan Fátima Mitiko

Abstract excerpt

Host single nucleotide polymorphisms (SNPs) in different genes can play a role in chronic hepatitis C virus (HCV) infection and influence the presence of hepatic fibrosis and comorbidities such as hepatic steatosis. We assessed the combined effect of SNPs in the PNPLA3, MTTP, TM6SF2, and IFNL3/IFNL4 genes in 288 Brazilian patients who were chronically infected with HCV. Hepatic fibrosis was observed in 246...

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Identifiers

PMID: 32147132
DOI: 10.1016/j.diagmicrobio.2020.115025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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