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Article

AdeR protein regulates adeABC expression by binding to a direct-repeat motif in the intercistronic spacer.

Microbiological research - 1 Feb 2016

Chang Tein-Yao, Huang Bo-Jun, Sun Jun-Ren, Perng Cherng-Lih, Chan Ming-Chin, Yu Cheng-Ping, Chiueh Tzong-Shi

Abstract excerpt

Overexpression of the efflux pump AdeABC is associated with tigecycline resistance of multi-drug resistant Acinetobacter baumannii (MDRAB). A two-component regulatory system, sensor AdeS and regulator AdeR proteins regulate the pump. However, the detailed mechanism of the AdeR protein to enhance the expression of adeABC operon is not well defined. We illustrated the biological characteristics of AdeR proteins by...

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Identifiers

PMID: 26805619
DOI: 10.1016/j.micres.2015.11.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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