Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel tigecycline resistance mechanisms in Acinetobacter baumannii mediated by mutations in adeS, rpoB and rrf.

Emerging microbes & infections - 1 Dec 2021

Hua Xiaoting, He Jintao, Wang Jingfen, Zhang Linghong, Zhang Linyue, Xu Qingye, Shi Keren, Leptihn Sebastian, Shi Yue, Fu Xiaoting, Zhu Pengfei, Higgins Paul G, Yu Yunsong

Abstract excerpt

Acinetobacter baumannii is an important pathogen in hospital acquired infections. Although tigecycline currently remains a potent antibiotic for treating infections caused by multidrug resistant A. baumannii (MDRAB) strains, reports of tigecycline resistant isolates have substantially increased. The resistance mechanisms to tigecycline in A. baumannii are far more complicated and diverse than what has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acinetobacter baumannii
Share to Acinetobacter Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anti-Bacterial Agents

Share to Bacterial Proteins

Share to Drug Resistance, Bacterial

Share to Microbial Sensitivity Tests

Share to RNA, Ribosomal, 5S

Share to Tigecycline

Source

Open in PubMed Open full text

Identifiers

PMID: 34170209
DOI: 10.1080/22221751.2021.1948804
PMCID: PMC8274536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel tigecycline resistance mechanisms in Acinetobacter baumannii mediated by mutations in adeS, rpoB and rrf.PMID 34170209Read ↗

A truncated AdeS kinase protein generated by ISAba1 insertion correlates with tigecycline resistance in Acinetobacter baumannii.Semantic proximity Read ↗

Role of the BaeSR two-component system in the regulation of Acinetobacter baumannii adeAB genes and its correlation with tigecycline susceptibilitySemantic proximity Read ↗

The Mechanism of Tigecycline Resistance in Acinetobacter baumannii under Sub-Minimal Inhibitory Concentrations of TigecyclineSemantic proximity Read ↗

Resistance associated genomic variations for moderate level tigecycline resistance evolution in Acinetobacter baumannii.Semantic proximity Read ↗

Mechanisms of Resistance, Clonal Expansion, and Increasing Prevalence of Acinetobacter baumannii Strains Displaying Elevated Tigecycline MIC Values in Latin America.Semantic proximity Read ↗

Molecular Characterization of Tigecycline Non-Susceptibility among Extensively Drug-Resistant Acinetobacter baumannii Isolates of Clinical Origin.Semantic proximity Read ↗

Role of efflux pumps in reduced susceptibility to tigecycline in Acinetobacter baumanniiSemantic proximity Read ↗

Correlation of RND efflux pump expression and AdeRS mutations in tigecycline-resistant Acinetobacter baumannii from Thai clinical isolatesSemantic proximity Read ↗

The distribution of mutations and hotspots in transcription regulators of resistance-nodulation-cell division efflux pumps in tigecycline non-susceptible Acinetobacter baumannii in China.Semantic proximity Read ↗

The tRNA methyltransferase TrmB is critical for Acinetobacter baumannii stress responses and pulmonary infectionSemantic proximity Read ↗

Inactivation of AdeABC and AdeIJK efflux pumps elicits specific nonoverlapping transcriptional and phenotypic responses in Acinetobacter baumannii.Semantic proximity Read ↗

Contribution of EmrAB efflux pumps to colistin resistance in Acinetobacter baumannii.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.