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Article

Single asparagine to arginine mutation allows PerR to switch from PerR box to fur box.

ACS chemical biology - 20 Mar 2015

Caux-Thang Christelle, Parent Aubérie, Sethu Ramakrishnan, Maïga Arhamatoulaye, Blondin Geneviève, Latour Jean-Marc, Duarte Victor

Abstract excerpt

Fur family proteins, ubiquitous in prokaryotes, play a pivotal role in microbial survival and virulence in most pathogens. Metalloregulators, such as Fur and PerR, regulate the transcription of genes connected to iron homeostasis and response to oxidative stress, respectively. In Bacillus subtili...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25486128
DOI: 10.1021/cb500783g

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25486128-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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