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Overexpression of the <i>adeB</i> Gene in Clinical Isolates of Tigecycline-Nonsusceptible <i>Acinetobacter baumannii</i> without Insertion Mutations in <i>adeRS</i>

10 Aug 2010

Abstract excerpt

Thirteen clinical isolates of multidrug-resistant Acinetobacter baumannii resistant to carbapenems (MRAB-C) with tigecycline nonsusceptibility were collected from individual patients in this study. None of the 13 isolates shared the same strain characteristics in molecular typing. All of them showed increased adeB transcription, as predicted. However, none of these tigecycline-nonsusceptible MRAB-C isolates were...

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PMID: 20696871
DOI: 10.1128/aac.00414-10

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