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Article

Phenotype microarray analysis of the AdeRS two-component system in Acinetobacter baumannii.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Dec 2017

Sun J-R, Chiang Y-S, Shang H-S, Perng C-L, Yang Y-S, Chiueh T-S

Abstract excerpt

Acinetobacter baumannii is a nosocomial pathogen capable of resistance to multiple antimicrobials. The AdeRS two-component system (TCS) is associated with antimicrobial resistance by controlling the AdeABC efflux pump. To elucidate modulation by AdeRS, we made an A. baumannii mutant lacking the AdeRS TCS and characterized it using phenotype microarray (PM) analysis. After disrupting the adeRS operon, lower...

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PMID: 28741095
DOI: 10.1007/s10096-017-3066-9

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