Article
Genetic Variability of AdeRS Two-Component System Associated with Tigecycline Resistance in XDR-Acinetobacter baumannii Isolates.
Current microbiology - 1 Jul 2015
Montaña S, Vilacoba E, Traglia G M, Almuzara M, Pennini M, Fernández A, Sucari A, Centrón D, Ramírez M S
Abstract excerpt
The emergence of tigecycline resistance has increased in the last years. Although tigecycline-resistant Acinetobacter baumannii isolates were described all over the world, few reports regarding the molecular basis of this resistance are available. It has been recognized that the overexpression of AdeABC efflux pump is related to the tigecycline-resistant phenotype. In 37 clinical A. baumannii isolates we first...
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