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Article

The Histone Chaperone FACT Contributes to DNA Replication-Coupled Nucleosome Assembly.

Cell reports - 9 Feb 2016

Yang Jiayi, Zhang Xu, Feng Jianxun, Leng He, Li Shuqi, Xiao Junyu, Liu Shaofeng, Xu Zhiyun, Xu Jiawei, Li Di, Wang Zhongshi, Wang Jingyang, Li Qing

Abstract excerpt

DNA replication-coupled (RC) nucleosome assembly is mediated by histone chaperones and is fundamental for epigenetic inheritance and maintenance of genomic integrity. The mechanisms that promote this process are only partially understood. Here, we show that the histone chaperone FACT (facilitates chromatin transactions), consisting of Spt16 and Pob3, promotes newly synthesized histone H3-H4 deposition. We...

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Identifiers

PMID: 26804921
DOI: 10.1016/j.celrep.2015.12.096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Histone Chaperone FACT Contributes to DNA Replication-Coupled Nucleosome Assembly.PMID 26804921Read ↗

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